I-Chamomile extract
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incazelo2
Ulwazi oluyisisekelo
Igama Lomkhiqizo: I-Chamomile extract
Ukubukeka: Impuphu noma i-granular ensundu kuya kophuzi
Ukupakisha Okujwayelekile: 25kg/isigubhu
Ukuncibilika: Ncibilikisa emanzini kanye ne-ethanol.
Izici Zomthombo Nezitshalo:
Igama Lesayensi:
I-chamomile yesiJalimane: I-Matricaria chamomilla L. (isici samafutha abalulekile aluhlaza okwesibhakabhaka)
I-chamomile yamaRoma: I-Chamaemelum nobile L. (iphunga elifana ne-apula)
Izingxenye Zokwelapha: Amakhanda ezimbali (avunwa lapho eqhakaza ngokugcwele ekuseni)
Ukusatshalaliswa: IYurophu, iNyakatho Afrika, iShayina (iGansu/Xinjiang)
Izici Eziyinhloko:
Izimbali ze-white ray + izimbali ze-yellow disc, i-hold conical center
Uhlobo lwesiJalimane lukhipha uwoyela obalulekile oluhlaza okwesibhakabhaka uma luchotshoziwe (umkhiqizo we-chamazulene oxidation)
Okujwayelekile: CP2020, JP, Kwenziwe Amakhasimende
Izingxenye Ezisebenzayo Eziyinhloko
1. Ama-Compounds Abalulekile E-Bioactive
Ikilasi | Ama-Compounds Amele | Ububanzi Bokuqukethwe | Izinzuzo Eziyinhloko |
Amafutha Aguquguqukayo | i-α-Bisabolol | 15-45% | Ukulwa nokuvuvukala (ukuvinjelwa kwe-COX-2) |
I-Chamazulene* | 1-15% | I-antioxidant, ilwa nokungezwani komzimba (ukuzinza kwamaseli e-mast) | |
Ama-Flavonoid | I-Apigenin | 0.5-3.0% | I-sedative (ukuguqulwa kwama-receptor e-GABA) |
I-Luteolin | 0.3-1.5% | Ukulwa nokuvuvukala (ukuvinjelwa kwe-NF-κB) | |
AmaSesquiterpenes | I-Matricin** | 0.2-1.2% | I-Spasmolytic (isiphumuli semisipha esibushelelezi) |
Ama-Polysaccharides | I-Arabinogalactan (AGP) | 3-8% | Ukuguqulwa kwamasosha omzimba (ukusebenza kwe-macrophage) |
Qaphela: I-Chamazulene ikhona njenge-matricin ezitshalweni ezintsha, ukuguqula ngesikhathi sokuhluzwa I-Matricin iyisandulela se-chamazulene
2. Imiphumela Yokubambisana:
I-α-Bisabolol + Zinc: ↑50% isivinini sokulungisa isikhumba
I-Apigenin + i-Glycine: ukudambisa okuthuthukisiwe okungu-2 ×
Ukuhlanzeka Okuphezulu
100% Yemvelo
Ihambisana nezindinganiso
Ukunikeza okuzinzile
Ikhwalithi iqinisekisiwe
Izicelo Ezihlukahlukene
Ukulungiswa Kwesikhumba Okulwa Nokuvuvukala
Izindlela: vimbela i-5-LOX, kunciphisa ukukhiqizwa kwe-leukotriene B4
Khulisa ukubonakaliswa kwe-EGF
Imininingwane Yezokwelapha: ukhilimu ongu-1% uthuthukisa izimpawu ze-eczema ngo-68% (uma kuqhathaniswa no-41% we-hydrocortisone)
Ukuvikelwa Kokugaya Ukudla
i-nhibit H. pylori (MIC=50μg/mL)
Ukuqeda ubuhlungu besisu se-IBS (ukusebenza kahle kwezokwelapha okungu-72%)
Imiphumela Yokudambisa
Izinkambu Zohlelo Lokusebenza Okuphezulu okuluhlaza okotshani
1. Imithi:
● Ukwelashwa Kwesikhumba: I-Atopic dermatitis, ukuqubuka kwenabukeni (indlela ehlukile ye-steroid)
● I-Neurology: Ukukhathazeka okuncane, usizo lokulala (nge-valerian)
2. Ukudla Okusebenzayo:
● Itiye lokuphumula: Lithuthukisa ukulala (↓25% amaphuzu e-PSQI)
● Impilo ye-GI: Iqeda i-dyspepsia yokusebenza
3. Izimonyo:
● Ama-serum aduduzayo: Alungisa isithiyo sesikhumba (↓40% TEWL)
● Ukunakekelwa kwengane: Amafomula angacasuli (ama-microemulsion e-pH5.5)
Ukuqamba Okusha Kwezobuchwepheshe
I-Nanoencapsulation (↑3× ukungena kwesikhumba)
I-Biosynthetic chamazulene (ukubonakaliswa kwemvubelo)
Izinhlelo Zokusebenza Ezintsha
Ukunakekelwa komlomo: Yelapha i-oral mucositis (izivivinyo zeSigaba III)
Impilo yezilwane ezifuywayo: Izifutho zokuqeda ukukhathazeka zezinja/amakati
Iziqondiso Zokusebenzisa
Isilinganiso Esinconywayo
Isicelo | Ukwakheka | Ukugxila | Ubude besikhathi |
Ukuvuvukala kwesikhumba | Ukhilimu we-topical | 1-2% | Amaviki ama-2-4 |
Ukungalali | Umlomo | 300-500mg/ngosuku | Inyanga eyi-1-3 |
Ukungagayeki kahle kokudla | Itiye | 2g/200ml amanzi ashisayo | Njengoba kudingeka |
Izinyathelo zokuzivikela
Nciphisa amafutha abalulekile (kunconywa
Ukuhlolwa kokuzwela kwe-photosensitivity (lawula ukungcola kwe-furanocoumarin)
Ngicela ungithumelele i-imeyili futhi ungathola okwengeziwe okufunayo.
Njengomkhiqizo wentengo, imininingwane, i-MOA, i-MSDS, ishadi lokugeleza, imininingwane yokupakisha, isikhathi sokuthumela, isikhathi sokukhokha, isevisi ngemuva kokuthengisa njalo njalo.
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