Ifa kanye Nokusungula Izinto Ezikhishwe Ezitshalweni Embonini Yezemithi

Kuwo wonke umlando omude wokulwa kwesintu nezifo, imithi yendabuko yaseShayina ibilokhu idlala indima ebalulekile ekuvimbeleni nasekwelapheni izifo. Kusukela kumafomula ezitshalo aqoshwe ezincwadini zasendulo kuya emithini yesimanje emisha, izingcezu zezitshalo zithatha isikhundla esivelele embonini yezokwelapha ngenxa yezithako zazo zemvelo ezisebenzayo kanye nemiphumela yazo eyingqayizivele yezokwelapha. Namuhla, ngokuthuthuka okuqhubekayo kobuchwepheshe, izingcezu zezitshalo ziyashintsha kusukela ekusetshenzisweni kwendabuko ziye esigabeni esisha sentuthuko entsha, zifaka amandla amasha ekunakekelweni kwezempilo emhlabeni jikelele.

Izithako Zezitshalo—Isisekelo Sendabuko Semboni Yezemithi

Emkhakheni wokuthuthukiswa kwemithi, imikhiqizo yokukhishwa kwezitshalo idlala indima ebalulekile.

I-Icaritin, ekhishwe ekhambi lemvelo i-Epimedium, ivunyelwe ukumaketha eShayina ekwelapheni i-hepatocellular carcinoma ethuthukisiwe ngokusebenzisa izivivinyo zemitholampilo ezilawulwa ngokuqinile.

I-Camptothecin, umuthi omele ukulwa nomdlavuza, okhishwe ezimpandeni ze-Nothapodytes pittosporoides (Oliv.) Sleumer, indlela esebenza ngayo ukuvimbela ukwanda kwamaseli esimila futhi ibangele i-apoptosis ngokuvimbela i-topoisomerase I (TOPO I), kanye ne-derivative yayo, i-7-Ethyl-10-hydroxycamptothecin, isebenza njengesikhungo esibalulekile ekukhiqizweni komuthi wokulwa nomdlavuza i-Irinotecan Hydrochloride (CPT-11). I-Chenlv Herb ifinyelele ekukhiqizweni kwe-camptothecin ngezinga lezimboni ngomkhiqizo waminyaka yonke odlula u-3,000 kg.

I-Palmatine chloride iyi-alkaloid ekhishwe eziqwini ze-Fibraurea recisa Pierre. inemiphumela emihle yokulwa namagciwane kanye ne-antibacterial, futhi ithuthukisa i-phagocytosis yama-leukocyte, futhi ivame ukusetshenziswa ekwelapheni ukuvuvukala kwabesifazane, i-enteritis, kanye nezifo zokuhlinzwa. Izifundo zemitholampilo zibonise ukuthi i-palmatine chloride ehlanganiswe ne-levofloxacin ifinyelela izinga lokwelapha elifinyelela ku-87.23% le-endometritis.

I-Diosmin inemiphumela yokulwa nokuvuvukala ngemithambo yegazi, inhlanganisela ye-diosmin namanye ama-flavonoid, ikakhulukazi i-hesperidin, ithole ukuthi iphumelela kakhulu ekwelapheni ukungasebenzi kahle kwemithambo yegazi okungapheli kanye nama-hemorrhoids, ngaleyo ndlela ibeka isibonelo esihle sokusebenzisana kwezidakamizwa.

Ukuthuthukiswa Okusha Kwezingcezu Zezitshalo Embonini Yezemithi

Ukuze kugwenywe ukutheleleka ngamagciwane kanye nemiphumela emibi enobuthi ehlotshaniswa nokusetshenziswa kwezinto eziphilayo ukulungisa amaphutha ethambo, kwasungulwa i-microsphere ehlanganisiwe enezidakamizwa ezimbili ye-berberine-naringin enezakhiwo zokulwa namagciwane kanye ne-osteogenic osteogenic ocwaningweni. I-Berberine hydrochloride, isithako semvelo esikhishwe emithini yendabuko yaseShayina iCoptis chinensis Franch, iBerberis soulieana Schneid. noma iPhellodendron chinense Schneid. , enemisebenzi eminingi yokulwa namagciwane. I-Naringin iyisithako esiyinhloko esisebenzayo se-Drynaria fortunei (Kunze) J.Sm., umuthi wendabuko waseShayina wokuqinisa izinso nokuqinisa amathambo, ongalawula ngempumelelo ukusebenza kwamathambo futhi ukhuthaze ukulungiswa kokulimala kwamathambo. Lo muthi we-microsphere ogcwele i-composite uthola imiphumela emibili yokulwa namagciwane kanye ne-osteogenic ngokukhulula kancane kancane izithako ezisebenzayo zemithi emibili yendabuko yaseShayina engenhla, uhlinzeka ngezinto ezintsha zokwelapha izifo zamathambo ezithelelekile.

Umkhuba Wokuthuthukiswa Kwemboni Yokukhipha Izitshalo

Ikusasa lezicucu zezitshalo emakethe yemithi lizobonisa izitayela ezintathu ezinkulu:

1. Amafomula enziwe ngendlela yomuntu siqu azokhula abe 35% yesabelo semakethe;

2. Ukuhlanganiswa kwezinto ezintsha phakathi kwemithi yemvelo kanye nebhayoloji yokwenziwa;

3. Ukuhlolwa kwe-compound esebenzayo okunamandla e-AI kuzonciphisa imijikelezo ye-R&D ngo 50%.

Ngenzuzo ye Izinhlobo ezingu-30,000 zezinsiza zezitshalo, iShayina ikulungele ukuthuthukisa ukuncintisana komhlaba wonke emikhakheni efana nokulwa nomdlavuza kanye nezifo eziwohlokayo. Ngo-2030, isilinganiso sokusetshenziswa kwezithako zezitshalo emkhakheni wezokwelapha sizodlula AmaRandi ayizigidigidi eziyi-15.