Ukusetshenziswa kwezithako zezitshalo ekudleni kwezilwane: amandla aguqula impilo yemvelo

Kusukela i-EU yavimbela ngokuphelele ukusetshenziswa kwama-antibiotic njengabagqugquzeli bokukhula ngo-2006, isidingo somhlaba wonke sezinye izindlela siye saba siphuthumayo kakhulu. Kusukela ekufuyweni kwezilwane ezifuywayo kanye nezinkukhu kuya ekuphathweni kwempilo yezilwane ezifuywayo, izithasiselo zezitshalo ziye zavela njengohlobo lwezithasiselo zokudla ezisebenzayo, eziphephile, ezizinzile, nezilawulekayo, ezihlinzeka ngesisombululo esiluhlaza nesiqhubekayo sokufuywa kwezilwane zanamuhla ngenxa yezici zazo zokungabi nemiphumela emibi kakhulu, ukumelana nemithi okuncane, kanye nensalela encane.

Izinhlobo Eziyinhloko Nezithako Ezisebenzayo Zezingcezu Zezitshalo

Izithako zezitshalo zingahlukaniswa ngokuhlelekile ngokuya ngomthombo, ukwakheka kanye nenqubo yokukhipha:

● Ngokwengxenye yesitshalo: Ama-Rhizomes (isib. I-Astragalus, i-Glycyrrhiza), amaqabunga (isib. Itiye, iRosemary), izithelo (isib. I-Citrus, imbewu yamagilebhisi), amakhambi aphelele (isib. I-Echinacea, i-Mint).

● Ngokusho kwezithako ezikhishwe: ama-polyphenols (ama-flavonoid, ama-tannins), ama-terpenoid (amafutha abalulekile, ama-saponins), ama-alkaloid (i-berberine, i-piperine), ama-polysaccharides (ama-astragalus polysaccharides, ama-lentinuns polysaccharides).

● Ngokusho kokuncibilika: izingcezu ezincibilika emanzini (ama-polysaccharides, ama-polyphenols), izingcezu ezincibilika emafutheni (amafutha abalulekile, imibala).

Izinto ezisebenzayo eziyinhloko kanye nemisebenzi yazo:

● Ama-polyphenols: ama-polyphenols etiye (i-antioxidant), ama-isoflavones e-soy (ama-prebiotic), ama-Proanthocyanidins (alwa nokuvuvukala).

● Uwoyela oguquguqukayo: i-thymol (i-antimicrobial), i-carvacrol (umgqugquzeli wokukhula), i-eucalyptol (impilo yokuphefumula).

● Ama-Polysaccharides: i-β-glucan (ukuvuselela amasosha omzimba), ama-fructooligosaccharides (isenzo sangaphambi kwe-biotic), i-mannan oligosaccharide (ukumuncwa kwe-pathogen).

Imisebenzi Eyinhloko kanye Nemiphumela Yezingcezu Zezitshalo Ekudleni Kwezilwane

● Ilwa namagciwane, ilwa nokuvuvukala futhi iqinisa amasosha omzimba

Izithako zezitshalo zithola imiphumela yokulwa namagciwane engenobuthi noma engeyona enobuthi ngokuphazamisa ulwelwesi lwamaseli ebhaktheriya, ukuvimbela umsebenzi we-enzyme, noma ukuphazamisa ukusebenza kwe-metabolism yama-microorganisms abangela izifo. Isibonelo, isithako sikaStephania singavimbela i-β-lactamase kanye ne-Staphylococcus aureus, okungcono kune-ampicillin; Isithako sikagalikhi sivimbela i-endometritis ngokuvimbela amagciwane esibelethweni. Emkhakheni wezilwane ezifuywayo, isithako sikaMonk izithelo singanciphisa ukwakheka kwezinto ezibangela ukuvuvukala, kuyilapho uwoyela we-Oregano ohlanganiswe nama-antibiotics uthuthukisa kakhulu izinga lokuphulukiswa kwe-escherichia coli. Ngaphezu kwalokho, ama-polysaccharides ezitshalo (isb., ama-polysaccharides e-astragalus) athuthukisa kakhulu ukuzivikela komzimba ngokusebenzisa ama-macrophages nokukhuthaza ukwanda kwama-lymphocyte e-T/B.

● Ukuvimbela ukushiswa kwe-oxidation kanye nokulwa nokucindezeleka

Ama-flavonoid nama-polyphenol ezitshalweni avikela amaseli ekulimaleni kwe-oxidative ngokukhipha ama-free radical kanye nokunciphisa i-lipid peroxidation. Isibonelo, ama-tea polyphenol nama-proanthocyanidins angathuthukisa umsebenzi we-superoxide dismutase (SOD) kanye ne-catalase (CAT), anciphise izinhlobo ze-oxygen ezisebenzayo. Ezifundweni zezinja ezifuywayo, ama-green tea polyphenols avimbele ukuhlukaniswa kwama-adipocyte futhi anciphisa ingozi yokukhuluphala ngokulawula ukuvezwa kwamaprotheni ahlobene nokusetshenziswa kwamafutha emzimbeni. Okwamanje, ezivivinyweni zezinkukhu ezibeka amaqanda, i-Artemisia extract yathuthukisa kakhulu amandla e-antioxidant ama-egg yolk futhi yandisa isikhathi sawo sokuhlala eshalofini.

● Impilo yamathumbu kanye nokulawulwa kwezinto eziphilayo ezincane

Izithako zezitshalo zithuthukisa imiphakathi yamagciwane amathumbu ngokuvimbela amabhaktheriya ayingozi nokukhuthaza ukwanda kwama-probiotic. Isibonelo, izithako ezivela ezitshalweni zeCinnamomum zinganciphisa umsebenzi we-urease ne-uricase, futhi zinciphise ukukhishwa kwe-ammonia. Izithako ze-Yucca kanye ne-fructooligosaccharides (FOS) zisiza ukulawula ibhalansi yamagciwane ezinjeni nasemakatini, zinciphise ama-metabolites ayingozi njenge-ammonia ne-histamine. Ngaphezu kwalokho, ama-polysaccharides ezitshalo asebenza njengezinto eziyisisekelo zokubilisa amagciwane, akhiqiza ama-fatty acid amafushane akhuthaza ukwanda kwamaseli e-epithelial emathunjini futhi athuthukise ukusebenza kahle kokumuncwa kwezakhamzimba. Ezivivinyweni zamathole ezingulube, ingxube ye-carvacrol kanye ne-cinnamaldehyde yandise kakhulu umsebenzi we-pepsin futhi yanciphisa uhudo.

● Ukukhuthaza ukukhula nokuguqulwa kokudla

Izithako zezitshalo zikhuthaza ukukhula kwezilwane ngokuthuthukisa ukunambitheka kokudla, kwandise umsebenzi wama-enzyme okugaya ukudla kanye nokulawula ukukhiqizwa kwama-hormone. Isibonelo, uwoyela obalulekile we-star anise ukhulisa kakhulu ukuphakama kwe-intestinal villus kanye nokudla kwezilwane; i-cinnamon extract ibambezela izilonda zamathumbu futhi ithuthukise ukusetshenziswa kokudla. Ezifundweni eziphathelene namakati afuywayo, ama-proanthocyanidins avimbela ukwanda kwamaseli amafutha futhi anciphise izinga lamafutha emzimbeni ngokulawula izakhi zofuzo ezihlobene nokusetshenziswa kwamafutha.

Ukusetshenziswa Okuyingqayizivele Kwezingcezu Zezitshalo Emikhiqizweni Yokudla Kwezilwane

● Ukufuya imfuyo kanye nezinkukhu: ubuchwepheshe obuyinhloko bokufaka esikhundleni sama-antibiotic

Ngaphansi kwesizinda "sokudla okungenama-antibiotic", izingcezu zezitshalo sezibe yisiqondiso esibalulekile kwezobuchwepheshe bokufaka esikhundleni sama-antibiotic. Isibonelo, isingcezu seqabunga le-Eucommia ulmoides, esicebile nge-chlorogenic acid kanye nama-flavonoid e-Eucommia, singathatha indawo yama-antibiotic ukukhuthaza ukukhula kwezingulube; isingcezu se-Dandelion sithuthukisa ukumelana negciwane lesifo saseNewcastle emaphuphuneni, kwehlisa amazinga okufa. Ekukhiqizeni kwezinkukhu ezizalayo, izingcezu ze-Lonicera japonica kanye nezingcezu ze-Turmeric zinganciphisa izinga lamaqanda angenamagobolondo futhi zithuthukise impilo ye-oviduct. Ngaphezu kwalokho, amafutha abalulekile (uwoyela we-oregano), ama-alkaloid (i-berberine, i-artemisinin, i-sanguinarine) athuthukisa impilo yamathumbu ngokusebenzisa imisebenzi ye-antioxidant, antibacterial kanye ne-antiparasitic. Izingcezu zezitshalo ezisusa ukushisa (isb. i-Scutellaria baicalensis extract, i-Honeysuckle extract) zingathuthukisa ngempumelelo ukusebenza kwezinkomo ezicindezelwe ukushisa.

● Ukudla okunempilo kwezilwane ezifuywayo: ukulawulwa okunembile kwezinkomba zezempilo

Izithako zezitshalo zibonise imiphumela ebalulekile ekubhekaneni nezinkinga ezifana nokukhuluphala kanye nokuvuvukala kwamathumbu ezinjeni ezifuywayo. Isithako se-Ginkgo biloba singanciphisa isisindo somzimba kanye nesilinganiso samafutha emzimbeni ezinjeni ezikhuluphele. Ama-Proanthocyanidins avimbela ukwanda kwamaseli amafutha ngokulawula izakhi zofuzo ezihlobene nokusetshenziswa kwamafutha emzimbeni. Ngaphezu kwalokho, isithako se-yucca singaguqula i-microbiota yamathumbu ezinjeni nasemakati, sinciphise ama-metabolites ayingozi (njenge-ammonia ne-histamine) futhi sithuthukise iphunga lendle. Ukudla kwezilwane ezifuywayo noma ukudla okulula okuqukethe ama-polyphenols etiye eliluhlaza kungavimbela ukukhula kwamagciwane ayingozi emlonyeni, kunciphise i-plaque yamazinyo kanye ne-calculus yamazinyo, futhi kuvimbele izifo zomlomo njenge-periodontitis. Izithako zezitshalo ezicebile ngamavithamini nama-antioxidants, njenge-flaxseed extract, i-blueberry extract, ne-lecithin, zinikeza ukudla okunomsoco ezinweleni ezifuywayo, okwenza zibe mnene futhi zikhanye.

● Izilwane ezifuywayo kanye nokufuywa kwezinhlanzi: amasimu okusetshenziswa asafufusa

Ezitshalweni zezilwane ezidla inyama, izithako zezitshalo (ezifana ne-yucca saponins) zingalawula ukuvutshelwa kwe-rumen futhi zithuthukise ukusetshenziswa kwe-nitrogen. Ekufuyweni kwezinhlanzi, izithako zamaqabunga e-Eucommia ulmoides zingathuthukisa ukuzivikela kwezinhlanzi futhi zinciphise amazinga okufa.

Izinselele Zokusebenzisa kanye Namasu Okuthuthukisa

● Izithiyo zobuchwepheshe ezikhona

Ukunambitheka: Amafutha abalulekile (isib. amafutha e-oregano) anganciphisa ukudla kwezilwane ezifuywayo.

Ukungahambisani: Imithamo ephezulu yama-tannins ivimbela umsebenzi we-protease futhi inciphise ukugayeka kwamaprotheni.

● Izixazululo kanye Nokuthambekela Kwentuthuko

I-Microencapsulation: I-Beta-cyclodextrin encapsulation ye-thymol inciphisa ukulahlekelwa okuguqukayo ngo-70% futhi yandisa isikhathi sokusebenza.

Ifomula Yesayensi: Inhlanganisela ye-curcumin ne-piperine yandisa ukutholakala kwezinto eziphilayo ngokuphindwe ka-20.

Izithako zezitshalo zinamathuba amaningi okusetshenziswa kanye namathuba amakhulu okuthuthukiswa emkhakheni wokudla kwezilwane kanye nokunakekelwa kwempilo. Ngocwaningo oluqhubekayo kanye nomkhuba, ubuchwepheshe bazo bokusetshenziswa buzothuthukiswa njalo ukuze buhlinzeke ngokusekelwa okuqinile kokukhuthaza intuthuko eluhlaza neqhubekayo yokufuya izilwane kanye nokukhiqiza ukudla okuphephile nokusezingeni eliphezulu okuvela ezilwaneni. Esikhathini esizayo, izithako zezitshalo kulindeleke ukuthi zidlale indima ebaluleke kakhulu embonini yokufuya izilwane.